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Chronic fatigue syndrome
The world medical literature in the last decade has seen a growing interest in the chronic fatigue syndrome (CFS), which occurs between 0.3 - 1% in the general population.

This syndrome is characterized by debilitating fatigue and exhaustion, that can not be explained by the diagnosed diseases. The causes of CFS are not sufficiently clear, and in this case there is no specific diagnostic test.
CFS is a disease of "thousands of names," it includes a number of ill-defined disorders and pathological conditions, including: neurasthenia, neurocirculatory dystonia, vazoregulative asthenia, vegetative neurosis, diencephalic and limbic encephalopathy, atypical multiple sclerosis, atypical migraine, muscular rheumatism, chronic brucellosis, postviral syndrome, chronic viral infection syndrome of Epstein-Barr, the immune dysfunction syndrome, environmental illness (Yerevan).
Contributing factors in the occurrence of chronic fatigue in the background of deregulated CNS are also considered: slow-infectious diseases, such as chlamydia, hepatitis, trauma, intoxication brought severe emotional or physical stress, loss of loved ones.

With long-term observation of patients in the neurological center of academic Avakyan with chronic fatigue syndrome, the following clinical symptoms were identified:
• The emergence of permanent or recurrent unexplained fatigue that persists after a night's sleep, rest, and significantly reduces the social, professional and personal activity of the patient for 6 months or more,
• Violations of the short-term memory and attention,
• presence of the "pathological" forgetfulness,
• periodic diffuse headache,
• Excessive irritability,
• abstraction,
• tendency to the depression,
• sleep structure disturbance.

The additional symptoms of the CFS are: increased body temperature (37,5 - 38,5 ° C), a sore throat, increase and morbidity of peripheral lymph nodes (axillary, cervical);
unexplained pain in muscles and joints without swelling or redness; feeling "bruised" after physical activity, constipation, rectal fractures.
Treatment and the Statistics

We have examined 354 patients with symptoms of CFS. Of them - 165 were men, 189 – were women. Age of the patients has been ranged from 28 to 55 years.

The diagnosis of CFS in all patients was confirmed in the independent health facilities, in the presence of five clinical symptoms, and at least 4 additional criteria, that were observed in each patient for 6 months or more.

Evaluation of the results of phytotreatment was carried out independently by patients with the help of special questionnaires and by the results of psychoneurological status, rheoencephalography, electroencephalography and NMRI of the brain, before and after the treatment. The evaluation was conducted in the dynamics (3, 6, 12 months).

After processing of the obtained data, the results of treatment were as follows:
• after 1 month of start of treatment in 66% of the total permanent fatigue phenomenon disappeared;
• in 84% - improved performance (mental), and in 81% - physical;
• in 78% - depressive mood has disappeared;
• in 52% - returned to normal night's sleep and daytime sleepiness disappeared;
• in 46% - unexplained pain in throat disappeared;
• in 37% - returned to normal body temperature;
• for more than half of the patients the tolerance to psycho-emotional overload has increased.

The mechanism of action

From the medicinal plants by phytomicro-spherical method active ingredients (lecithin, unsaturated fatty acids, amino acids, neurotransmitters, vitamins E, D, B1, B2, B6, PP, C, biologically active plant-iodine, trace elements Mg, K, Ca, Cu, Re, Se, P) were isolated.

The main properties of these biologically active substances are:

1) The vasodilating action;

2) normalization of the liquoproduction and improvement of the venous outflow;

3) anti-sclerotic and cardioprotective effect through inhibition LPNP oxidation;

4) psychotropic and neuroprotective effects;

5) regulation of all types of the metabolism (fat, carbohydrate, protein, water and salt);

6) immunocorrecting action aimed at the non-specific body defense.